Silicosis is a progressive pneumoconiosis characterised by interstitial fibrosis following publicity to silica mud. The function of metabolic dysregulation in the pathogenesis of silicosis has not been investigated in element. This study aimed to establish totally different metabolic features in the plasma of patients with silicosis and dust-exposed workers with out silicosis in metabolomics research. Patients with silicosis, dust-exposed workers (DEWs) with out silicosis and age-matched wholesome controls have been recruited in a case-control study. The metabolomics analyses by ultra-high efficiency liquid chromatography-mass spectrometry have been performed. Distinct metabolic features (DMFs) have been recognized in the pilot study and have been validated in the validation study.
The enriched signalling pathways of these DMFs have been decided. The capacity of DMFs to discriminate amongst the teams was analysed by way of receiver working attribute (ROC) curves. The correlations between DMFs and medical features have been additionally explored. Twenty-nine DMFs and 9 DMFs have been detected and had the similar development in the pilot study and the validation study in the plasma of the DEW and silicosis teams, respectively. Sphingolipid metabolism was the main metabolic pathway in the DEWs, and arginine and proline metabolism was related with silicosis. Twenty DMFs in the DEWs and three DMFs in the patients with silicosis confirmed a discriminatory capacity with ROC curve evaluation.
The abundance of kynurenine was greater in Stage III silicosis than in Stage I or Stage II silicosis. L-arginine and kynurenine have been each negatively correlated with the share of compelled very important capability predicted in silicosis. Distinct metabolic features in the plasma of DEWs and the patients with silicosis have been discovered to be totally different. Sphingolipid metabolism and arginine and proline metabolism have been recognized as the main metabolic pathway in the DEW and silicosis teams, respectively. L-arginine and kynurenine have been correlated with the severity of silicosis. We developed and in contrast two liquid chromatography (LC) strategies, one with UV/Visible spectrophotometric detection (HPLC) and the different with mass spectrometric detection (LC-MS), for quantifying very-long chain fatty acids (VLCFA) in human plasma. Association of VLCFA with numerous cardiovascular threat elements have been evaluated.
Fasting blood samples have been collected from 541 human volunteers (242 males and 299 girls; imply age ±SD, 58.9 ±12.four years), together with 429 and 112 people with and with out hypertriglyceridemia, respectively. Esterified VLCFA have been saponified and derivatized with 2-nitrophenylhydrazine. Separation of VLCFA species was achieved with C4 Mightysil column (HPLC) and Ascentis Express Phenyl-Hexyl column (LC-MS) adopted by spectrophotometric and selected-reaction monitoring mode of mass spectrometric detection, respectively.
Combined genomic and proteomic approaches reveal DNA binding websites and interplay companions of TBX2 in the growing lung
Tbx2 encodes a transcriptional repressor implicated in the improvement of quite a few organs in mouse. During lung improvement TBX2 maintains the proliferation of mesenchymal progenitors, and therefore, epithelial proliferation and branching morphogenesis. The pro-proliferative perform was traced to direct repression of the cell-cycle inhibitor genes Cdkn1a and Cdkn1b, in addition to of genes encoding WNT antagonists, Frzb and Shisa3, to extend pro-proliferative WNT signaling.
Despite these essential molecular insights, we nonetheless lack data of the DNA occupancy of TBX2 in the genome, and of the protein interplay companions concerned in transcriptional repression of goal genes. Our information recommend that TBX2 interacts with homeobox and HMG-box transcription elements in addition to with the NuRD chromatin reworking complicated to repress transcription of anti-proliferative genes in the pulmonary mesenchyme. This supplies distinctive mechanistic perception into cerebrovascular illness and potential drug targets. Overall, we offer a highly effective useful resource to study the features of mind ECM and spotlight a particular function for mind vascular ECM in cerebral vascular illness.
We used chromatin immunoprecipitation (ChIP)-sequencing and expression analyses to establish genomic DNA-binding websites and transcription models immediately regulated by TBX2 in the growing lung. Moreover, we purified TBX2 containing protein complexes from embryonic lung tissue and recognized potential interplay companions by subsequent liquid chromatography/mass spectrometry. The interplay with candidate proteins was validated by immunofluorescence, proximity ligation and particular person co-immunoprecipitation analyses.
We recognized Il33 and Ccn4 as extra direct goal genes of TBX2 in the pulmonary mesenchyme. Analyzing TBX2 occupancy information unveiled the enrichment of 5 consensus sequences, three of which match T-box binding parts. The remaining two correspond to a excessive mobility group (HMG)-box and a homeobox consensus sequence motif. We discovered and validated binding of TBX2 to the HMG-box transcription issue HMGB2 and the homeobox transcription issue PBX1, to the heterochromatin protein CBX3, and to numerous members of the nucleosome reworking and deacetylase (NuRD) chromatin reworking complicated together with HDAC1, HDAC2 and CHD4.
Global proteomic evaluation of extracellular matrix in mouse and human mind highlights relevance to cerebrovascular illness
The extracellular matrix (ECM) is a key interface between the cerebrovasculature and adjoining mind tissues. Deregulation of the ECM contributes to a broad vary of neurological problems. However, regardless of this significance, our understanding of the ECM composition stays very restricted primarily because of difficulties in its isolation. To handle this, we developed an strategy to extract the cerebrovascular ECM from mouse and human autopsy regular mind tissues. We then used mass spectrometry with off-line high-pH reversed-phase fractionation to extend the protein detection.
Custom Peptide Synthesis (>70% antigen grade; mass spec, hplc (mg-kg size, price based upon peptide size: 2-100 aa) |
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| PEP-70 | Alpha Diagnostics | 1 | Ask for price |
Breast disease spectrum tissue array, including pathology grade, TNM and clinical stage, 20 cases/20 cores |
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| BR201 | BioCoreUSA | row: 4; column: 5; cores: 20; cases: 20 | EUR 216 |
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Description: Breast disease spectrum tissue microarray, containing 5 cases of invasive carcinoma of no special type, 2 invasive lobular carcinoma, 2 medullary carcinoma, 1 Paget's disease, 3 adenoma, 5 hyperplasia, 2 adjacent normal breast tissue, single core per case |
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Breast disease spectrum tissue array, including pathology grade, TNM and clinical stage, 47 cases/101 cores, replacing BR1003b |
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| BR1003c | BioCoreUSA | row: 10; column: 11; cores: 101; cases: 47 | EUR 306 |
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Description: Breast disease spectrum tissue microarray, containing 10 cases of each hyperplasia, ductal intraepithelial neoplasia, invasive carcinoma of no special type and invasive lobular carcinoma, duplicated cores per case, plus 7 normal breast tissue, triplicated cores per case |
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Brain disease spectrum (brain cancer progression) tissue array, including pathology grade, TNM and clinical stage, 79 cases/80 cores |
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| NCT801 | BioCoreUSA | row: 8; column: 10; cores: 80; cases: 79 | EUR 306 |
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Description: Brain disease spectrum (brain cancer progression) microarray, containing 16 cases of astrocytoma, 6 oligodendroglioma, 5 each of ependymoma and medulloblastoma, 30 meningioma, 2 choroid plexus papilloma, 8 each of adjacent normal tissue (1 matched with carcinoma) and normal tissue, single core per block |
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Innovative Grade US Origin Bovine Muscle Masseter |
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| IGBOMSCMTF | Innovative research | each | EUR 133 |
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Description: Innovative Grade US Origin Bovine Muscle Masseter |
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Innovative Grade US Origin Bovine Muscle Masseter |
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| IGBOMSCMTP | Innovative research | each | EUR 133 |
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Description: Innovative Grade US Origin Bovine Muscle Masseter |
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Innovative Grade US Origin Bovine Muscle Masseter |
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| IGBOMSCMTS | Innovative research | each | EUR 210 |
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Description: Innovative Grade US Origin Bovine Muscle Masseter |
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Innovative Grade US Origin Bovine Muscle Masseter |
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| IGBOMSCMTZ | Innovative research | each | EUR 210 |
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Description: Innovative Grade US Origin Bovine Muscle Masseter |
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Vermiform appendix disease spectrum (vermiform appendix cancer progression) tissue array, including pathology grade, 50 cases/100 cores |
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| DAP1001 | BioCoreUSA | row: 10; column: 10; cores: 100; cases: 50 | EUR 306 |
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Description: Vermiform appendix disease spectrum tissue microarray, containing 4 cases of carcinoid , 8 adenocarcinoma, 1 each of metastatic carcinoid and tubular adenoma, 30 inflammation, 6 appendix tissue, duplicated cores per case |
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Prostate Specific Antigen Std Grade Antigen |
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| VAng-Cr3891-1mg | Creative Biolabs | 1 mg | EUR 604.8 |
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Description: Prostate Specific Antigen Std Grade Antigen, Host/Source: Human Seminal Fluid. The purity is detected by salt precipitation. |
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Pancreas disease spectrum (pancreatic cancer progression) with pancreas tissue array, including pathology grade, TNM and clinical stage, 96 cases/192 cores, replacing PA2081c |
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| DPA2081d | BioCoreUSA | row: 12; column: 16; cores: 192; cases: 96 | EUR 546 |
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Description: Pancreas disease spectrum (pancreatic cancer progression) with pancreas tissue microarray, containing 35 cases adenocarcinoma, 3 adenosquamous carcinoma, 1 neuroendocrine tumor, 5 metastatic carcinoma, 10 pancreas islet cell tumor, 8 inflammation, 24 adjacent normal pancreas tissue, 10 normal pancreas tissue, duplicated cores per case |
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Research Grade Maslimomab |
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| MBS1563351-01mg | MyBiosource | 0.1mg | EUR 375 |
Research Grade Maslimomab |
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| MBS1563351-1mg | MyBiosource | 1mg | EUR 1090 |
Research Grade Maslimomab |
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| MBS1563351-5x1mg | MyBiosource | 5x1mg | EUR 4590 |
Research Grade Masavibart |
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| MBS1564040-01mg | MyBiosource | 0.1mg | EUR 375 |
Research Grade Masavibart |
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| MBS1564040-1mg | MyBiosource | 1mg | EUR 1090 |
Research Grade Masavibart |
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| MBS1564040-5x1mg | MyBiosource | 5x1mg | EUR 4590 |
2‐BROMO‐5‐HYDROXY BENZYLDEHYDE 99.5 % SPECIAL GRADE |
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| 602007 | Survival Technologies | each | Ask for price |
Research Grade Spesolimab |
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| MBS1563967-01mg | MyBiosource | 0.1mg | EUR 375 |
Research Grade Spesolimab |
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| MBS1563967-1mg | MyBiosource | 1mg | EUR 1090 |
Research Grade Spesolimab |
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| MBS1563967-5x1mg | MyBiosource | 5x1mg | EUR 4590 |
Tryptone (MB grade) (Casitose, MB grade) |
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| RM7707-500G | EWC Diagnostics | 1 unit | EUR 50.21 |
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Description: Tryptone (MB grade) (Casitose, MB grade) |
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DCCD (Crystalline Mass) |
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| MBS406588-100g | MyBiosource | 100g | EUR 160 |
DCCD (Crystalline Mass) |
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| MBS406588-500g | MyBiosource | 500g | EUR 330 |
DCCD (Crystalline Mass) |
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| MBS406588-5x500g | MyBiosource | 5x500g | EUR 1425 |
Spectropho Std Fe 1mg/L in 5% HNO3 - 500ML |
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| OPS-FE1-500 | Scientific Laboratory Supplies | 500ML | EUR 259.98 |
Spectropho Std Mn 5mg/L in 5% HNO3 - 500ML |
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| OPS-MN5-500 | Scientific Laboratory Supplies | 500ML | EUR 224.73 |
Spectropho Blank 0.1M HCl - 100ML |
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| RSPEC00521 | Scientific Laboratory Supplies | 100ML | EUR 286.2 |
Bovine ECGF (Crude Extract, cell culture grade) Specialities |
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| 300-090 | ReliaTech | 6 mg | EUR 31.5 |
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Description: Endothelial cell growth factor (ECGF) is an extract of bovine brain containing growth promoting factors for vascular endothelial cells of mammalian origin. ECGF has also been reported to be beneficial as a media supplement for the fusion and growth of hybridoma cells in monoclonal antibody production. Endothelial cell growth factor is prepared using a modification of the method of Maciag, et al. (1979) lyophilized from a sterile solution containing NaCl and streptomycin sulfate. Endothelial cells from human umbilical vein (HUVEC) can be established as primary cultures by traditional methods. The serial propagation of these cells has proved to be difficult. The long-term propagation of these cells in vitro can be achieved with an extract prepared from bovine brain. The introduction of a fibronectin or collagen matrix to the cell culture system allows cultivating endothelial cells at clonal densities. With ECGF, the FCS requirement can be reduced. Heparin potentiates the mitogenic activity of crude preparations of ECGF. ECGF has also been reported to eliminate the need for feeder cells in the clonal growth of hybridomas and other cell types. |
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Bovine ECGF (Crude Extract, cell culture grade) Specialities |
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| 300-090-5 | ReliaTech | 5x6 mg | EUR 147 |
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Description: Endothelial cell growth factor (ECGF) is an extract of bovine brain containing growth promoting factors for vascular endothelial cells of mammalian origin. ECGF has also been reported to be beneficial as a media supplement for the fusion and growth of hybridoma cells in monoclonal antibody production. Endothelial cell growth factor is prepared using a modification of the method of Maciag, et al. (1979) lyophilized from a sterile solution containing NaCl and streptomycin sulfate. Endothelial cells from human umbilical vein (HUVEC) can be established as primary cultures by traditional methods. The serial propagation of these cells has proved to be difficult. The long-term propagation of these cells in vitro can be achieved with an extract prepared from bovine brain. The introduction of a fibronectin or collagen matrix to the cell culture system allows to cultivate endothelial cells at clonal densities. With ECGF, the FCS requirement can be reduced. Heparin potentiates the mitogenic activity of crude preparations of ECGF. ECGF has also been reported to eliminate the need for feeder cells in the clonal growth of hybridomas and other cell types. |
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Spectroquant COD test - EACH |
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| WAT1080 | Scientific Laboratory Supplies | EACH | EUR 124.85 |
Spectropho Std Sol. Fe 6mg/L in 5% HNO3 - 500ML |
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| OPS-FE6-500 | Scientific Laboratory Supplies | 500ML | EUR 224.73 |
Spectropho Blank 0.1M HCl in Cuv - EACH |
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| RSPEC0052 | Scientific Laboratory Supplies | EACH | EUR 525.15 |
Porcine ECGF (Crude Extract, cell culture grade) Specialities |
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| 300-092 | ReliaTech | 6 mg | EUR 31.5 |
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Description: Endothelial cell growth factor (ECGF) is an extract of porcine brain containing growth promoting factors for vascular endothelial cells of mammalian origin. ECGF has also been reported to be beneficial as a media supplement for the fusion and growth of hybridoma cells in monoclonal antibody production. Endothelial cell growth factor is prepared using a modification of the method of Maciag, et al. (1979) lyophilized from a sterile solution containing NaCl and streptomycin sulfate. Endothelial cells from human umbilical vein (HUVEC) can be established as primary cultures by traditional methods. The serial propagation of these cells has proved to be difficult. The long-term propagation of these cells in vitro can be achieved with an extract prepared from bovine brain. The introduction of a fibronectin or collagen matrix to the cell culture system allows to cultivate endothelial cells at clonal densities. With ECGF, the FCS requirement can be reduced. Heparin potentiates the mitogenic activity of crude preparations of ECGF. ECGF has also been reported to eliminate the need for feeder cells in the clonal growth of hybridomas and other cell types. |
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Porcine ECGF (Crude Extract, cell culture grade) Specialities |
|||
| 300-092-5 | ReliaTech | 5x6 mg | EUR 147 |
|
Description: Endothelial cell growth factor (ECGF) is an extract of porcine brain containing growth promoting factors for vascular endothelial cells of mammalian origin. ECGF has also been reported to be beneficial as a media supplement for the fusion and growth of hybridoma cells in monoclonal antibody production. Endothelial cell growth factor is prepared using a modification of the method of Maciag, et al. (1979) lyophilized from a sterile solution containing NaCl and streptomycin sulfate. Endothelial cells from human umbilical vein (HUVEC) can be established as primary cultures by traditional methods. The serial propagation of these cells has proved to be difficult. The long-term propagation of these cells in vitro can be achieved with an extract prepared from bovine brain. The introduction of a fibronectin or collagen matrix to the cell culture system allows to cultivate endothelial cells at clonal densities. With ECGF, the FCS requirement can be reduced. Heparin potentiates the mitogenic activity of crude preparations of ECGF. ECGF has also been reported to eliminate the need for feeder cells in the clonal growth of hybridomas and other cell types. |
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Hyaluronidase Grade I (Molecular Biology Grade) |
|||
| CE174 | GeneOn | 1 g | EUR 232.8 |
Hyaluronidase Grade I (Molecular Biology Grade) |
|||
| CE175 | GeneOn | 5 g | EUR 920.4 |
100% Magic acid spectrograde |
|||
| M00052 | Pfaltz & Bauer | 25G | EUR 13518.28 |
Spectropho Std 1.0 (8301) w/ Backgr Sol. - 125ML |
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| OPS1 | Scientific Laboratory Supplies | 125ML | EUR 1026.69 |
Spectropho Std 2.0 w/ Backgr Sol. - 125ML |
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| OPS2 | Scientific Laboratory Supplies | 125ML | EUR 684.46 |
Spectropho Std 20.0 w/ Backgr Sol. - 125ML |
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| OPS20 | Scientific Laboratory Supplies | 125ML | EUR 747.62 |
Spectropho Std 3.0 w/ Backgr Sol. - 125ML |
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| OPS3 | Scientific Laboratory Supplies | 125ML | EUR 684.46 |
Spectropho Std 30.0 w/ Backgr Sol. - 125ML |
|||
| OPS30 | Scientific Laboratory Supplies | 125ML | EUR 762.31 |
Spectropho Std 4.0 w/ Backgr Sol. - 125ML |
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| OPS4 | Scientific Laboratory Supplies | 125ML | EUR 1142.73 |
Spectropho Std 5.0 (8305) w/ Backgr Sol. - 125ML |
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| OPS5 | Scientific Laboratory Supplies | 125ML | EUR 691.8 |
Spectropho Std 6.0 w/ Backgr Sol. - 125ML |
|||
| OPS6 | Scientific Laboratory Supplies | 125ML | EUR 684.46 |
Spectropho Std 7.0 (8307) w/ Backgr Sol. - 125ML |
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| OPS7 | Scientific Laboratory Supplies | 125ML | EUR 684.46 |
Spectropho Std 8.0 w/ Backgr Sol. - 125ML |
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| OPS8 | Scientific Laboratory Supplies | 125ML | EUR 684.46 |
Spectropho Pot Dichro A/T Std 60mg/L |
|||
| RSPEC00241 | Scientific Laboratory Supplies | 100ML | EUR 444.6 |
UV/Vis Spectrophotomer 7205 - EACH |
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| SPE2236 | Scientific Laboratory Supplies | EACH | EUR 3801.6 |
S6+ Visible Scanning Spectro |
|||
| SPE9204 | Scientific Laboratory Supplies | EACH | EUR 2471.52 |
ICI LC 1205/1210 Spectrophotometer D2 Lamp - EACH |
|||
| LD-ICI-101 | Scientific Laboratory Supplies | EACH | EUR 884.25 |
Acetone for HPLC & UV Spectroscopy, 99.9% |
|||
| 11340 | Sisco Laboratories | 500 ml | EUR 3.42 |
|
Description: Part A |
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Toluene for HPLC & UV Spectroscopy, 99.8% |
|||
| 29490 | Sisco Laboratories | 500 ml | EUR 3.22 |
|
Description: Part A |
|||
Benzene for HPLC & UV Spectroscopy, 99.8% |
|||
| 36823 | Sisco Laboratories | 500 ml | EUR 2.6 |
|
Description: Part A |
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Formamide for UV Spectroscopy, 99% |
|||
| 83256 | Sisco Laboratories | 500 ml | EUR 8.21 |
|
Description: Part A |
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Spectroph Background Sol. - 125ML |
|||
| OPSB | Scientific Laboratory Supplies | 125ML | EUR 96.94 |
Spectropho Pot Dichro A/T Std 60mg/L in Cuv - PK2 |
|||
| RSPEC-EP0060 | Scientific Laboratory Supplies | PK2 | EUR 2777.5 |
Spectropho Pot Dichro A/T Std 60mg/L - 100ML |
|||
| RSPEC-EP00601 | Scientific Laboratory Supplies | 100ML | EUR 556.68 |
Spectropho Pot Dichro A/T Std 600mg/L - 100ML |
|||
| RSPEC-EP00611 | Scientific Laboratory Supplies | 100ML | EUR 556.68 |
Spectropho Pot Dichro A/T Std 50mg/L - 100ML |
|||
| RSPEC00201 | Scientific Laboratory Supplies | 100ML | EUR 286.2 |
Spectropho Pot Dichro A/T Std 20mg/L - 100ML |
|||
| RSPEC00221 | Scientific Laboratory Supplies | 100ML | EUR 526.5 |
Spectropho Pot Dichro A/T Std 40mg/L - 100ML |
|||
| RSPEC00231 | Scientific Laboratory Supplies | 100ML | EUR 286.2 |
Spectropho Pot Dichro A/T Std 80mg/L - 100ML |
|||
| RSPEC00251 | Scientific Laboratory Supplies | 100ML | EUR 286.2 |
Spectropho Pot Dichro A/T Std 100mg/L - 100ML |
|||
| RSPEC00261 | Scientific Laboratory Supplies | 100ML | EUR 286.2 |
WPA S800+ Spectrophotometer |
|||
| SPE9200 | Scientific Laboratory Supplies | EACH | EUR 2144.34 |
Jenway 7410 spectrophotometer - EACH |
|||
| SPE4602 | Scientific Laboratory Supplies | EACH | EUR 6022.35 |
Jenway 7415 spectrophotometer - EACH |
|||
| SPE4604 | Scientific Laboratory Supplies | EACH | EUR 6716.25 |
Jenway 6850 Spectrophotometer - EACH |
|||
| SPE4626 | Scientific Laboratory Supplies | EACH | EUR 11487.15 |
Mass M2 Brass 1G |
|||
| BAL1650 | Scientific Laboratory Supplies | EACH | EUR 7.98 |
Mass M2 Brass 2G |
|||
| BAL1652 | Scientific Laboratory Supplies | EACH | EUR 7.98 |
1,4-Dioxane for HPLC & UV Spectroscopy, 99.9% |
|||
| 43294 | Sisco Laboratories | 500 ml | EUR 7.53 |
|
Description: Part A |
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n-Pentane for HPLC & UV Spectroscopy, 99% |
|||
| 49135 | Sisco Laboratories | 500 ml | EUR 8.21 |
|
Description: Part A |
|||
Carbinol for HPLC & UV Spectroscopy, 99.8% |
|||
| 63713 | Sisco Laboratories | 500 ml | EUR 2.53 |
|
Description: Part A |
|||
Ethyl Ether for HPLC & UV Spectroscopy, 99.9% |
|||
| 68329 | Sisco Laboratories | 500 ml | EUR 15.74 |
|
Description: Part A |
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Methanol for HPLC & UV Spectroscopy, 99.8% |
|||
| 79345 | Sisco Laboratories | 500 ml | EUR 2.53 |
|
Description: Part A |
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Pyridine for HPLC & UV Spectroscopy, 99.5% |
|||
| 83329 | Sisco Laboratories | 500 ml | EUR 8.21 |
|
Description: Part A |
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n-Heptane for HPLC & UV Spectroscopy, 99.5% |
|||
| 90731 | Sisco Laboratories | 500 ml | EUR 4.11 |
|
Description: Part A |
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Spectropho Pot Dichro A/T Std 600mg/L in Cuvs - PK2 |
|||
| RSPEC-EP0061 | Scientific Laboratory Supplies | PK2 | EUR 1636.24 |
Spectropho Pot Dichro A/T Std 10mg/L in Cuvs - PK2 |
|||
| RSPEC0018 | Scientific Laboratory Supplies | PK2 | EUR 1595.12 |
Spectropho Pot Dichro A/T Std 15mg/L in Cuvs - PK2 |
|||
| RSPEC0019 | Scientific Laboratory Supplies | PK2 | EUR 1595.12 |
Spectropho Pot Dichro A/T Std 50mg/L in Cuvs - PK2 |
|||
| RSPEC0020 | Scientific Laboratory Supplies | PK2 | EUR 1571.4 |
Spectropho Pot Dichro A/T Std 20mg/L in Cuvs - PK2 |
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| RSPEC0022 | Scientific Laboratory Supplies | PK2 | EUR 1571.4 |
Spectropho Pot Dichro A/T Std 40mg/L in Cuvs - PK2 |
|||
| RSPEC0023 | Scientific Laboratory Supplies | PK2 | EUR 1571.4 |
Spectropho Pot Dichro A/T Std 60mg/L in Cuvs - PK2 |
|||
| RSPEC0024 | Scientific Laboratory Supplies | PK2 | EUR 1571.4 |
Spectropho Pot Dichro A/T Std 80mg/L in Cuvs - PK2 |
|||
| RSPEC0025 | Scientific Laboratory Supplies | PK2 | EUR 1571.4 |
Spectropho Pot Dichro A/T Std 100mg/L in Cuvs - PK2 |
|||
| RSPEC0026 | Scientific Laboratory Supplies | PK2 | EUR 1571.4 |
Spectropho Blank 0.001M Perch Acid - 100ML |
|||
| RSPEC00511 | Scientific Laboratory Supplies | 100ML | EUR 526.5 |
XD 7000 Vis Spectrophotometer - EACH |
|||
| SPE2036 | Scientific Laboratory Supplies | EACH | EUR 6420.6 |
Libra Spectrophotometer S50 |
|||
| SPE4402 | Scientific Laboratory Supplies | EACH | EUR 7227.6 |
WPA S1200+ Spectrophotometer |
|||
| SPE9202 | Scientific Laboratory Supplies | EACH | EUR 2503.44 |
Mass M2 Brass 10G |
|||
| BAL1656 | Scientific Laboratory Supplies | EACH | EUR 9.12 |
Mass M2 Brass 20G |
|||
| BAL1658 | Scientific Laboratory Supplies | EACH | EUR 14.82 |
Mass M2 Brass 50G |
|||
| BAL1660 | Scientific Laboratory Supplies | EACH | EUR 18.24 |
Mass M2 Brass 500G |
|||
| BAL1666 | Scientific Laboratory Supplies | EACH | EUR 54.72 |
Mass Brass M2 1000G |
|||
| BAL1668 | Scientific Laboratory Supplies | EACH | EUR 79.8 |
Mass Brass M2 2000G |
|||
| BAL1670 | Scientific Laboratory Supplies | EACH | EUR 145.92 |
ODN 2336- Type A human specific TLR 9 agonist-antigen grade |
|||
| ODN2336-1 | Alpha Diagnostics | 1 mg | EUR 781.2 |
ODN 2336- Type A human specific TLR 9 agonist-antigen grade |
|||
| ODN2336-5 | Alpha Diagnostics | 5 mg | EUR 2389.2 |
ODN 2336 -Type A human specific TLR 9 agonist-antigen grade |
|||
| ODN2336-F | Alpha Diagnostics | Custom | Ask for price |
SpectroDirect for Waste Water - EACH |
|||
| WAT2038 | Scientific Laboratory Supplies | EACH | EUR 5387.56 |
Isooctane for HPLC & UV Spectroscopy, 99.5% |
|||
| 68930 | Sisco Laboratories | 500 ml | EUR 9.37 |
|
Description: Part A |
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Shimadzu Spectrophotr D2 Lamp - EACH |
|||
| LMP2030 | Scientific Laboratory Supplies | EACH | EUR 369.9 |
Spectropho A/T Std Blank 0.005M Sulph Acid - 100ML |
|||
| RSPEC-EP00751 | Scientific Laboratory Supplies | 100ML | EUR 556.68 |
Spectropho Blank 0.001M Perch Acid in Cuv - EACH |
|||
| RSPEC0051 | Scientific Laboratory Supplies | EACH | EUR 525.15 |
PhotoLab 7100 spectrophotometer - EACH |
|||
| WAT5109 | Scientific Laboratory Supplies | EACH | EUR 6638.98 |
PhotoLab 7600 spectrophotometer - EACH |
|||
| WAT5110 | Scientific Laboratory Supplies | EACH | EUR 9256.38 |
Hexokinase (yeast) Grade S (HK (Yeast) Grade S) |
|||
| MBS682045-10KUnits | MyBiosource | 10KUnits | EUR 1485 |
Hexokinase (yeast) Grade S (HK (Yeast) Grade S) |
|||
| MBS682053-500Units | MyBiosource | 500Units | EUR 360 |
Hexokinase (yeast) Grade S (HK (Yeast) Grade S) |
|||
| MBS682073-2500Units | MyBiosource | 2500Units | EUR 570 |
OPEF01495-1MG - Prostate Specific Antigen (PSA) Antigen Std Grade |
|||
| OPEF01495-1MG | Aviva Systems Biology | 1mg | EUR 227 |
Calibration Mass 100g E2 - EACH |
|||
| BAL1712 | Scientific Laboratory Supplies | EACH | EUR 178.2 |
Calibration Mass 200g E2 - EACH |
|||
| BAL1714 | Scientific Laboratory Supplies | EACH | EUR 229.5 |
Calibration Mass 500g E2 - EACH |
|||
| BAL1716 | Scientific Laboratory Supplies | EACH | EUR 432 |
Spectrophotometer 6305 Jenway - EACH |
|||
| 635001 | Scientific Laboratory Supplies | EACH | EUR 5057.1 |
Paraffin liquid, For IR Spectroscopy |
|||
| GRM1136-100ML | EWC Diagnostics | 1 unit | EUR 6.93 |
|
Description: Paraffin liquid, For IR Spectroscopy |
|||
Paraffin liquid, For IR Spectroscopy |
|||
| GRM1136-500ML | EWC Diagnostics | 1 unit | EUR 20.07 |
|
Description: Paraffin liquid, For IR Spectroscopy |
|||
SV100 Spectrocolorimeter - EACH |
|||
| WAT2078 | Scientific Laboratory Supplies | EACH | EUR 3780.69 |
Acetone-d6 for NMR spectroscopy, 99.5 Atom %D |
|||
| 12972 | Sisco Laboratories | 10 ml | EUR 73.89 |
|
Description: Part A |
|||
Ethyl Acetate for HPLC & UV Spectroscopy, 99.9% |
|||
| 26614 | Sisco Laboratories | 500 ml | EUR 3.01 |
|
Description: Part A |
|||
Chloroform for HPLC & UV Spectroscopy, 99.8% |
|||
| 30792 | Sisco Laboratories | 500 ml | EUR 3.08 |
|
Description: Part A |
|||
Toluene-d8 for NMR spectroscopy, 99.5 Atom %D |
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| 85590 | Sisco Laboratories | 10 ml | EUR 93.26 |
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Description: Part A |
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Spectropho Nicotinic Acid A/T Std 6mg/L - 100ML |
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| RSPEC00271 | Scientific Laboratory Supplies | 100ML | EUR 287.88 |
Spectropho Bandwidth Std Blank - 100ML |
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| RSPEC00531 | Scientific Laboratory Supplies | 100ML | EUR 286.2 |
This recognized greater than 1000 proteins in the ECM-enriched fraction, with > 66% of the proteins being widespread between the species. We report 147 core ECM proteins of the human mind vascular matrisome, together with collagens, laminins, fibronectin and nidogens. We subsequent used community evaluation to establish the connection between the mind ECM proteins and cerebrovascular ailments. We discovered that genes associated to cerebrovascular ailments, resembling COL4A1, COL4A2, VCAN and APOE have been considerably enriched in the cerebrovascular ECM community.